Plant Transcription Factor Database
Previous version: v3.0
Solanum tuberosum
NF-YA Family
Species TF ID Description
PGSC0003DMP400000545NF-YA family protein
PGSC0003DMP400000546NF-YA family protein
PGSC0003DMP400000547NF-YA family protein
PGSC0003DMP400000548NF-YA family protein
PGSC0003DMP400004388NF-YA family protein
PGSC0003DMP400004389NF-YA family protein
PGSC0003DMP400004390NF-YA family protein
PGSC0003DMP400004391NF-YA family protein
PGSC0003DMP400004392NF-YA family protein
PGSC0003DMP400004393NF-YA family protein
PGSC0003DMP400012163NF-YA family protein
PGSC0003DMP400012164NF-YA family protein
PGSC0003DMP400013016NF-YA family protein
PGSC0003DMP400013017NF-YA family protein
PGSC0003DMP400013018NF-YA family protein
PGSC0003DMP400014333NF-YA family protein
PGSC0003DMP400014334NF-YA family protein
PGSC0003DMP400018923NF-YA family protein
PGSC0003DMP400020925NF-YA family protein
PGSC0003DMP400020926NF-YA family protein
PGSC0003DMP400020927NF-YA family protein
PGSC0003DMP400036611NF-YA family protein
PGSC0003DMP400036612NF-YA family protein
PGSC0003DMP400037034NF-YA family protein
PGSC0003DMP400037694NF-YA family protein
PGSC0003DMP400048896NF-YA family protein
PGSC0003DMP400048897NF-YA family protein
PGSC0003DMP400048898NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982